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Base
| Nom | Latifa BOUSARGHIN |
| Grade | |
| Equipe | |
| Adresse | CHU Pontchaillou – 2 rue Henri Le Guilloux – 35033 Rennes Cedex |
| Téléphone | |
| Skills |
– Bacteriology : pathogenic (Salmonella), commensal strains (Bacteroides fragilis, Roseburia intestinalis, Akkermansia). -Virology : Human papillomavirus VLPs – Cell culture: – Hela, Cos-7, Caco-2, HT29 MTX, Rajib, NCI-H716 cells – immune cells : dendritic and Langerhans cells – Monoculture or 2D culture – Organoïds – Mice model of Salmonella infection (BALB/C)
– using gut microbiota and natural extracts – to fight ESKAPE strains and Salmonella with an hypermutator phenotype
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| Research topics and scientific objectives |
Caracterization of gut microbiota bacteria and their impact on health : gut barrier, immune and endocrine function. – Development of new antibiotics to fight resistance bacteria : ANR and Institut Carnot Agrifood transition projects – Human papillomavirus vaccine
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| Education and main positions held |
-Since 2007 , associated Professor in microbiology (bacteriology and virology), Faculty of Pharmacy, Rennes 1 university 2002 PhD in Virology, “ Genes vectorization using virus-like particles of human papillomavirus and polyomavirus: application to the detection of neutralizing antibodies.”, University of Tours, France
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| Current projects | – Caracterization of gut microbiota bacteria and their impact on health : gut barrier, immune and endocrine function. – Development of new antibiotics to fight resistance bacteria : ANR and Institut Carnot Agrifood transition projects |
| Selected publications | bousarghin L-search Results-Pubmed (nih.gov) : https://pubmed.ncbi.nlm.nih.gov/?term=bousarghin+L |