• English

Latifa BOUSARGHIN

Afficher le profil

Base

Nom

Latifa BOUSARGHIN

Grade

MCU

Equipe

METHER

Email

latifa.bousarghin@univ-rennes1.fr

Adresse

CHU Pontchaillou – 2 rue Henri Le Guilloux – 35033 Rennes Cedex

Téléphone

02-23-23-48-98

Skills

 

  • Pathogens/host interactions

– Bacteriology : pathogenic (Salmonella), commensal strains (Bacteroides fragilis, Roseburia intestinalis, Akkermansia).

-Virology : Human papillomavirus VLPs

– Cell culture:

– Hela, Cos-7, Caco-2, HT29 MTX, Rajib, NCI-H716 cells

– immune cells : dendritic and Langerhans cells

– Monoculture or 2D culture

– Organoïds

– Mice model of Salmonella infection (BALB/C)

  •       Development of new antibiotics

                 – using gut microbiota and natural extracts

– to fight ESKAPE strains and Salmonella with an hypermutator phenotype

 

Research topics and scientific objectives

 

Caracterization of gut microbiota bacteria and their impact on health : gut barrier, immune and endocrine function.

– Development of new antibiotics to fight resistance bacteria : ANR and Institut Carnot Agrifood transition projects

– Human papillomavirus vaccine

 

Education and main positions held

 

-Since 2007 , associated Professor in microbiology (bacteriology and virology), Faculty of Pharmacy, Rennes 1 university

2002 PhD in Virology, “ Genes vectorization using virus-like particles of human papillomavirus and polyomavirus: application to the detection of neutralizing antibodies.”, University of Tours, France

 

Current projects

– Caracterization of gut microbiota bacteria and their impact on health : gut barrier, immune and endocrine function.

– Development of new antibiotics to fight resistance bacteria : ANR and Institut Carnot Agrifood transition projects

Selected publications

bousarghin L-search Results-Pubmed (nih.gov) : https://pubmed.ncbi.nlm.nih.gov/?term=bousarghin+L